Cook Biotech is now part of RTI Surgical.
See the press release about this acquisition for more information.

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Biodesign Scientific Monograph Series


A series of six scientific monographs exploring porcine small intestine submucosa (SIS) technology, and one of its applications, Biodesign® advanced tissue repair products. Topics addressed include the effects of cross-linking in biologic grafts, the effects of elastin in biologic grafts, constructive tissue remodeling in tissue repair, constructive inflammation in wound healing, biology of the extracellular matrix (ECM), and dynamic reciprocity and wound healing.


wounds, wound healing, dynamic reciprocity, cell, extracellular matrix (ECM), tissue remodeling, homeostasis, hemostasis, clot formation, inflammation, granulation, collagen, biomaterial, OASIS, Biodesign, tissue repair, natural cross-linking, chemical cross-linking, biologic grafts, cytotoxic, calcification, foreign body reaction, inflammation, encapsulation, vascularized, elastin, dermis, dermisbased biologic grafts, diastasis, small intestinal submucosa, SIS, hernia repair, open ventral hernia repair, recurrence, failure, tension, stiffness, strength, elasticity, scar tissue, synthetic meshes, crosslinked biologic grafts, bioresorbable materials, growth factors, glycoproteins, proteoglycans, reinforcement, soft tissue reinforcement, chronic inflammation, proliferation, granulation tissue, rejection response, foreign body response, glycosaminoglycans (GAGs), fibronectin, matrix metalloproteases (MMPs), cytokines, remodeling, burns, burn depth, total body surface area (TBSA), severity, severe burns, burn treatment, Lund-Browder chart, “Rule of Nines”, National Institutes of Health (NIH), first degree burn, second degree burn, third degree burn, fourth degree burn, superficial, superficial partial thickness, deep partial thickness, full thickness, advanced burn treatment, systemic response, local tissue response, challenges of burn treatment, pain, complications, burn progression, burn conversion, Jackson burn zone, zone of coagulation, zone of stasis, zone of hyperemia, education, Cook Biotech